>-D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE

В Makefile ничего похожего нет.
-------------------------------------
>А вообще не помню - если у mc есть configure - там надо поискать large_file_support

# ./configure -help
Usage: configure [options] [host]
Options: [defaults in brackets after descriptions]
Configuration:
  --cache-file=FILE       cache test results in FILE
  --help                  print this message
  --no-create             do not create output files
  --quiet, --silent       do not print `checking...' messages
  --version               print the version of autoconf that created configure
Directory and file names:
  --prefix=PREFIX         install architecture-independent files in PREFIX
                          [/usr/local]
  --exec-prefix=EPREFIX   install architecture-dependent files in EPREFIX
                          [same as prefix]
  --bindir=DIR            user executables in DIR [EPREFIX/bin]
  --sbindir=DIR           system admin executables in DIR [EPREFIX/sbin]
  --libexecdir=DIR        program executables in DIR [EPREFIX/libexec]
  --datadir=DIR           read-only architecture-independent data in DIR
                          [PREFIX/share]
  --sysconfdir=DIR        read-only single-machine data in DIR [PREFIX/etc]
  --sharedstatedir=DIR    modifiable architecture-independent data in DIR
                          [PREFIX/com]
  --localstatedir=DIR     modifiable single-machine data in DIR [PREFIX/var]
  --libdir=DIR            object code libraries in DIR [EPREFIX/lib]
  --includedir=DIR        C header files in DIR [PREFIX/include]
  --oldincludedir=DIR     C header files for non-gcc in DIR [/usr/include]
  --infodir=DIR           info documentation in DIR [PREFIX/info]
  --mandir=DIR            man documentation in DIR [PREFIX/man]
  --srcdir=DIR            find the sources in DIR [configure dir or ..]
  --program-prefix=PREFIX prepend PREFIX to installed program names
  --program-suffix=SUFFIX append SUFFIX to installed program names
  --program-transform-name=PROGRAM
                          run sed PROGRAM on installed program names
Host type:
  --build=BUILD           configure for building on BUILD [BUILD=HOST]
  --host=HOST             configure for HOST [guessed]
  --target=TARGET         configure for TARGET [TARGET=HOST]
Features and packages:
  --disable-FEATURE       do not include FEATURE (same as --enable-FEATURE=no)
  --enable-FEATURE[=ARG]  include FEATURE [ARG=yes]
  --with-PACKAGE[=ARG]    use PACKAGE [ARG=yes]
  --without-PACKAGE       do not use PACKAGE (same as --with-PACKAGE=no)
  --x-includes=DIR        X include files are in DIR
  --x-libraries=DIR       X library files are in DIR
--enable and --with options recognized:
  --disable-nls           do not use Native Language Support
  --with-included-gettext use the GNU gettext library included here
  --with-catgets          use catgets functions if available
  --with-x                use the X Window System
--with-xview              Use the XView toolkit
--with-xview-includes=path  Specifies XView includes directory
--with-xview-libraries=path  Specifies XView libraries directory
--with-xv-bindir=dir  Specifies directory where to install XView version
--with-sco                 Use this to turn on SCO-specific code
--with-sunos-curses        Used to force SunOS 4.x curses
--with-osf1-curses         Used to force OSF/1 curses
--with-vcurses[=incdir]    Used to force SysV curses
--with-gpm-mouse[=base-dir]  Compile with gpm mouse support
--with-ncurses[=base-dir]    Compile with ncurses/locate base dir
--with-hsc               Compile with support for the HSC firewall
--with-tk                  Use the Tk toolkit
--with-tk-includes=dir     Specifies the Tcl/Tk header directory
--with-tk-libraries=dir    Specifies the Tcl/Tk library directory
  --with-gnome-includes   Specify location of GNOME headers
  --with-gnome-libs       Specify location of GNOME libs
  --with-gnome            Specify prefix for GNOME files
--with-dusum               Support the du -s summaries
--with-termnet             If you want a termified net support
--with-subshell            If you want to use a concurrent shell
--with-debug               For use by developers only: activates -Wall and MAD
--with-efence              Developers only: activates -Wall and efence
--with-mmap                To force using the mmap call (AIX)
--with-terminfo            SLANG: Force usage of terminfo
--with-termcap             SLANG: Force usage of termcap
--with-included-slang      SLANG: use the SLang library included here
--with-slang               Compile with the slang screen manager
--with-vfs                 Compile with the VFS code
--with-edit                Define INTERNAL_EDIT
--with-netrc               Compile with ftp .netrc support
--with-ext2undel           Compile with ext2 undelete code

Ну и где ?